Table 2.
Expression of immunohistochemical markers and frequency of TP53 gene mutations
| Parameter | Number (n = 266) , n (%) | |
| Maspin expression in tumor core | Negative | 39 (14.66) |
| Cytoplasm | 125 (46.99) | |
| Mixed (nucleus+cytoplasm) | 85 (31.96) | |
| Nuclear | 17 (6.39) | |
| Maspin expression in the invasion front | Negative | 21 (7.90) |
| Cytoplasm | 0 (0) | |
| Mixed (nucleus+cytoplasm) | 201 (75.56) | |
| Nuclear | 44 (16.54) | |
| p53 – nuclear expression | Negative | 40 (15.04) |
| 5%-50% | 69 (25.94) | |
| > 50% | 157 (59.02) | |
| TP53 gene status | Wild-type | 176 (66.17) |
| Mutations | 90 (33.83) | |