TABLE 1.
Sensitization rates and skin inflammation scores in guinea pigs after the GPMT with TCE, TCA, and TCEOH
| Group | Number of guinea pigs (n) | Number of guinea pigs with different skin inflammation scores | Sensitization rate (%) | |||
|---|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | |||
| Blank | 5 | 5 | 0 | 0 | 0 | 0.0 |
| DNCB | 5 | 0 | 0 | 3 | 2 | 100.0 |
| TCE solvent control | 5 | 5 | 0 | 0 | 0 | 0.0 |
| TCEOH solvent control | 5 | 5 | 0 | 0 | 0 | 0.0 |
| TCA solvent control | 5 | 5 | 0 | 0 | 0 | 0.0 |
| TCE | 10 | 1 | 6 | 3 | 0 | 90.0 |
| TCEOH | 10 | 5 | 5 | 0 | 0 | 50.0 |
| TCA | 10 | 10 | 0 | 0 | 0 | 0.0 |
TCE solvent control: induced with olive and challenged with TCE.
TCEOH solvent control: induced with olive and challenged with TCEOH.
TCA solvent control: induced with saline and challenged with TCA.
Abbreviations: DNCB, 2,4‐dinitrochlorobenzene; GPMT, guinea pig maximization test; TCA, trichloroacetic acid; TCE, trichloroethylene; TCEOH; trichloroethanol.