Table 1.
Demographics and clinical characteristics.
| Variable | Control group (n = 89) | PACG group (n = 94) | p value |
|---|---|---|---|
| Age (year) | 57.03 ± 8.35 | 58.32 ± 13.51 | 0.437& |
| Gender (male/female) | 34/55 | 37/57 | 0.872∗ |
| BMI (m2/kg) | 22.94 ± 3.18 | 22.52 ± 2.97 | 0.348& |
| SBP (mm Hg) | 126.29 ± 9.10 | 124.52 ± 13.82 | 0.306& |
| DBP (mm Hg) | 73.99 ± 7.52 | 73.30 ± 9.46 | 0.589& |
| Smoking (yes/no) | 20/69 | 23/71 | 0.750∗ |
| Drinking (yes/no) | 22/67 | 24/70 | 0.899∗ |
| Number of topical glaucoma medications, n | |||
| 0 | — | 4 | — |
| 1-2 | — | 33 | — |
| >2 | — | 57 | — |
| IOP (mm Hg) | 13.04 ± 3.23 | 21.68 ± 14.36 | <0.001& |
| VCDR | — | 0.63 ± 0.23 | — |
| CCT (mm) | — | 545.34 ± 43.80 | — |
| ACD (cm) | — | 1.99 ± 0.51 | — |
| AL (cm) | — | 22.65 ± 1.41 | — |
| MD (dB) | — | 10.98 ± 7.42 | — |
| MS (dB) | — | 17.34 ± 7.45 | — |
| GPX (U/L) | 57.36 ± 9.67 | 56.30 ± 12.18 | 0.517& |
| GR (U/L) | 59.79 ± 11.57 | 62.43 ± 12.98 | 0.148& |
| SOD (U/mL) | 169.00 ± 38.44 | 140.99 ± 28.35 | <0.001& |
| TAS | 1.22 ± 0.16 | 0.98 ± 0.17 | <0.001& |
| MDA (umol/l) | 5.57 ± 4.49 | 30.69 ± 35.99 | <0.001& |
| H2O2 (umol/l) | 8.20 ± 6.25 | 18.03 ± 10.93 | <0.001& |
&Independent-samples t-test; #Mann-Whitney U test; ∗χ2 test. BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; IOP: intraocular pressure; VCDR: vertical cup-disc ratio; CCT: central corneal thickness; ACD: anterior chamber depth; AL: axial length; MD: visual field mean deviation; MS: visual field mean sensitivity; SOD: superoxide dismutase; TAS: total antioxidant status; H2O2: hydrogen peroxide; MDA: malondialdehyde; GPX: glutathione peroxidase; GR: glutathione reductase.