Table 2.

Variant Classifications

Variants	After Reassessment
		P	LP	VUS	LB	B	Not Categorized
Original	P	6[Link]	2	0	0	0	0
	LP	1	6[Link]	4[Link]	0	0	0
	VUS	0	0	64[Link] , [Link]	18	8	0
	LB	0	0	0	2[Link]	1	0
	B	0	0	0	0	2[Link]	0
	Not categorized	0	0	0	2	0	0

Variant classifications at the time of original testing and reclassification after applying current American College of Medical Genetics and Genomics and the Association for Molecular Pathology variant classification criteria. B indicates benign; LB, likely benign; LP, likely pathogenic; P, pathogenic; and VUS, variant of uncertain significance.

Variants that did not change and shaded boxes indicate variant reclassifications.

Four variants reclassified as VUS‐favor pathogenic.

Two VUS‐favor pathogenic.