. 2020 Jun 10;9(12):e014990. doi: 10.1161/JAHA.119.014990

Table 2.

Association Between Smoking Status and Incident Stroke From Visit 1 to 2015

Variable	Never Smokers	Past Smokers	Current Smokers	Current (1–19 Cigarettes/d)	Current (≥20 Cigarettes/d)
Stroke incidence, n/total (%)	105/3089	41/781	37/546	24/366	13/180
Stroke incidence, n/total (%)	(3.4)	(5.2)	(6.8)	(6.6)	(7.2)

Model	Smoking Status		Smoking Intensity
Model	Past vs Never Smokers	Current vs Never Smokers	Current (1–19 Cigarettes/d) vs Never Smokers	Current (≥20 Cigarettes/d) vs Never Smokers
Model 1	1.16 (0.81, 1.68)	2.57 (1.75, 3.79)^a ^, ^b	2.54 (1.62, 3.99)^a ^, ^b	2.65 (1.46, 4.80)^a ^, ^b
Model 2	1.10 (0.74, 1.64)	2.48 (1.60, 3.83)^a ^, ^b	2.28 (1.35, 3.86)^a ^, ^c	2.78 (1.47, 5.28)^a ^, ^c
Model 3	1.12 (0.75, 1.67)	2.44 (1.57, 3.78)^a ^, ^b	2.30 (1.37, 3.90)^a ^, ^c	2.62 (1.37, 5.01)^a ^,†

Values are given as hazard ratio (95% CI), unless otherwise indicated. Model 1, adjusted for age and sex. Model 2, model 1 plus education level, diabetes mellitus, systolic blood pressure, body mass index, hypertension, total cholesterol, fasting triglycerides, physical activity, and statin use. Model 3, model 2 plus CRP (C‐reactive protein).

The values are statistically significant.

P<0.05.

P<0.001.