Table 2.

Variants of Rhinophyma

Jansen and Plewig15
Group	Description
Glandular	Prominent hyperplasia of sebaceous glands Presence of Demodex mites Dense distribution of VIP-R-positive cells Presence of intermediate filaments and neuroglandular antigen
Fibrous	Diffuse hyperplasia of the connective tissue Variable sebaceous gland hyperplasia Massive deposits of actinically damaged elastotic material, vascular enlargement Absence of pilosebaceous structures Positive Factor XIII staining
Fibroangiomatous	Nose is copper-red to dark-red, enlarged, edematous, with presence of ectatic veins Presence of pustules Presence of fibrosis, telangiectasias, inflammatory lesions Less prominent sebaceous hyperplasia
Actinic	Nodular masses of elastic tissue Proliferation of sebaceous glands Dilated ducts Expression of inspissated sebum Presence of gram-positive coryneform bacteria and Demodex folliculorum Sparse distribution of yeast-like organisms

Abbreviation: VIP-R-positive, vasoactive intestinal peptide receptor.