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. 2020 Aug 20;40(8):1127–1133. [Article in Chinese] doi: 10.12122/j.issn.1673-4254.2020.08.09

4.

TOPS-1对小鼠血脂的影响

Effects of different doses of TOPS-1 on serum lipid levels in rats (Mean±SD, mmol/L)

Groups Dose (g/kg) TC TG LDL-C HDL-C
TC: Total cholesterol; TG: Triacylglycerol; LDL-C: Low-density lipoprotein cholesterol; HDL-C: High-density lipoprotein cholesterol. **P<0.01 vs normal group; ##P<0.01 vs model group.
Normal - 3.32±0.38 0.56±0.11 2.42±0.14 1.80±0.33
Model - 12.51±1.47** 8.43±0.67** 8.96±1.01** 0.97±0.24**
Low-dose 0.1 10.19±1.46 3.83±0.43## 7.64±2.19 1.11±0.33
Medium dose 0.2 8.71±1.05## 2.92±0.64## 5.85±1.13## 1.43±0.82
High-dose 0.4 10.22±1.34 4.74±1.88## 7.73±2.37 1.48±1.16
Control 5 pills/kg 10.38±0.97 3.86±0.35 7.48±1.26 1.90±0.50