4.
TOPS-1对小鼠血脂的影响
Effects of different doses of TOPS-1 on serum lipid levels in rats (Mean±SD, mmol/L)
| Groups | Dose (g/kg) | TC | TG | LDL-C | HDL-C |
| TC: Total cholesterol; TG: Triacylglycerol; LDL-C: Low-density lipoprotein cholesterol; HDL-C: High-density lipoprotein cholesterol. **P<0.01 vs normal group; ##P<0.01 vs model group. | |||||
| Normal | - | 3.32±0.38 | 0.56±0.11 | 2.42±0.14 | 1.80±0.33 |
| Model | - | 12.51±1.47** | 8.43±0.67** | 8.96±1.01** | 0.97±0.24** |
| Low-dose | 0.1 | 10.19±1.46 | 3.83±0.43## | 7.64±2.19 | 1.11±0.33 |
| Medium dose | 0.2 | 8.71±1.05## | 2.92±0.64## | 5.85±1.13## | 1.43±0.82 |
| High-dose | 0.4 | 10.22±1.34 | 4.74±1.88## | 7.73±2.37 | 1.48±1.16 |
| Control | 5 pills/kg | 10.38±0.97 | 3.86±0.35 | 7.48±1.26 | 1.90±0.50 |