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. 2020 Aug 20;40(8):1200–1206. [Article in Chinese] doi: 10.12122/j.issn.1673-4254.2020.08.19

1.

ESCC患者临床资料与NSG小鼠和BALB/c裸鼠移植瘤模型成瘤率的统计描述

Relationship between clinical characteristics of ESCC patients and tumor formation rate of NSG mice and BALB/c nude mice xenograft models

Factors Success Failure Total Rate(%) P
NSG BALB/c NSG BALB/c NSG BALB/c NSG BALB/c
P value: Success vs Failure.
Age (year)
 ≥60 10 4 7 11 17 58.82% 23.53% 0.853 0.456
  < 60 1 0 4 5 5 20% 0%
Gender
 Male 7 2 10 15 17 41.18% 11.76% 0.139 0.104
 Female 4 2 1 3 5 80% 40%
Staging
 Ⅰ-Ⅱ 4 1 6 9 10 40% 10% 0.412 0.174
 Ⅲ-Ⅳ 7 3 5 9 12 58.33% 25%
Differentiation
 Poor 2 0 1 3 3 66.67% 0% 0.326 0.371
 Moderate-poor 3 3 2 2 5 60% 60%
 Moderate 4 1 6 9 10 40% 10%
 High 1 0 3 4 4 25% 0%
Lymphnodemetastasis
 Yes 4 1 6 9 10 40% 10% 0.416 0.03
 No 7 3 5 9 12 58.3% 25%