Table 2.
The Basic Information of SNPs and Allele Frequencies in MAFLD Patients and Controls
| SNP | Allele Frequency | Genotype Frequency | HWE | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MAF | OR (95% CI) | P | Pcorr | P | Pcorr | |||||||
| rs6499640 | G/A | G/G | A/G | A/A | ||||||||
| Case | 1235/247 | 0.17 | 513 | 209 | 19 | 0.916 | ||||||
| Control | 1383/267 | 0.16 | 1.036 (0.857–1.252) | 0.715 | >1.000 | 576 | 231 | 18 | 0.875 | >1.000 | 0.652 | |
| rs1421085 | T/C | T/T | T/C | C/C | ||||||||
| Case | 1268/214 | 0.14 | 541 | 186 | 14 | 0.911 | ||||||
| Control | 1467/183 | 0.11 | 1.353 (1.095–1.671) | 0.005 | 0.03 | 649 | 169 | 7 | 0.014 | >1.000 | 0.539 | |
| rs8050136 | C/A | C/C | C/A | A/A | ||||||||
| Case | 1269/213 | 0.14 | 541 | 187 | 13 | 0.788 | ||||||
| Control | 1470/180 | 0.11 | 1.371 (1.109–1.695) | 0.004 | 0.024 | 652 | 166 | 7 | 0.012 | >1.000 | 0.6 | |
| rs3751812 | G/T | G/G | G/T | T/T | ||||||||
| Case | 1267/215 | 0.15 | 539 | 189 | 13 | 0.744 | ||||||
| Control | 1468/182 | 0.11 | 1.369 (1.108–1.691) | 0.004 | 0.024 | 650 | 168 | 7 | 0.011 | >1.000 | 0.559 | |
| rs9939609 | T/A | T/T | T/A | A/A | ||||||||
| Case | 1267/215 | 0.15 | 539 | 189 | 13 | 0.744 | ||||||
| Control | 1468/182 | 0.11 | 1.369 (1.108–1.691) | 0.004 | 0.024 | 650 | 168 | 7 | 0.011 | >1.000 | 0.559 | |
| rs9930506 | A/G | A/A | A/G | G/G | ||||||||
| Case | 1190/292 | 0.2 | 482 | 226 | 33 | 0.616 | ||||||
| Control | 1370/280 | 0.17 | 1.201 (1.001–1.439) | 0.048 | 0.288 | 564 | 242 | 19 | 0.043 | >1.000 | 0.501 | |
Abbreviations: SNP, single nucleotide polymorphisms; MAF, minor allele frequency; HWE, Hardy–Weinberg equilibrium; OR, odds ratio; CI, confidence interval; Pcorr, P value after Bonferroni correction.