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. 2020 Aug 11;15:5927–5949. doi: 10.2147/IJN.S254108

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© 2020 He et al.

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(A) In vitro PA/US/CEUS contrast images of A-FP NPs or A-P NPs at different concentrations. (B) PA intensity of A-FP NPs at different concentrations. (C and D) Gray values in US (B-mode) and CEUS imaging of A-FP NPs at different concentrations after Irradiation. (E) The phase change of A-FP NPs caused by laser irradiation and A-P NPs with no change (scale bars: 20 μm).

Abbreviations: FePc, iron(II) phthalocyanine; PA, photoacoustic; US, ultrasound; CEUS, contrast enhanced ultrasound; A-P NPs, AS1411-PLGA@PFP; A-FP NPs, AS1411-PLGA@FePc@PFP; FP NPs, PLGA@FePc@PFP.