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. 2020 Aug 11;15:5927–5949. doi: 10.2147/IJN.S254108

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© 2020 He et al.

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In vivo PTT treatment. (A) IR thermal images of MCF-7 tumor-bearing mice with various groups (control, A-FP NPs only, laser only, FP NPs combined with the laser, and A-FP NPs combined with the laser). (B) The temperature time curves of tumor sites in different groups by the thermal imager. (C) Photographs of changes in MCF-7 tumor-bearing mice of different groups were recorded by cameras every three days during the 21 days. (D) The body weight curves of MCF-7 tumor-bearing mice with various treatments during the 21 days. (E) Relative tumor growth curves of five groups after various treatments during the observation period. (Values are means ± s.d., n = 5, ****P < 0.0001).

Abbreviations: PTT, photothermal Therapy; A-FP NPs, AS1411-PLGA@FePc@PFP; FP NPs, PLGA@FePc@PFP.