Table 3.
Comparison of sub-MIC, MBIC, and MBEC of Ciprofloxacin Against Selected UPEC Strains
| Sample ID | Biofilm Analysis via TCP at 540 nm | Effect of Sub-Minimal and Higher Concentration of CIP on Biofilm Fomation | |||||
|---|---|---|---|---|---|---|---|
| Control | 1/2 MIC | 1/4MIC | 1/8 MIC | 1/16 MIC | MIC-b | MBIC (MRC) | |
| 168 | 0.617±0.22 | 1.550±0.86 | 0.5603±0.43 | 0.885±0.35 | 1.624±1.69 | 128 | >2048 |
| 169 | 0.6233±0.02 | 1.297±0.04 | 2.754±0.14 | 1.33±0.73 | 0.857±0.34 | 2048 | >2048 |
| 176 | 1.109±0.34 | 2.362±0.19 | 1.813±0.35 | 2.013±0.45 | 2.609±0.14 | 128 | >2048 |
| 181 | 0.870±0.08 | 1.023±0.15 | 1.703±0.48 | 1.889±1.13 | 1.779±0.35 | 512 | >2048 |
| 182 | 0.849±0.67 | 0.548±0.18 | 0.519±0.04 | 0.595±0.2 | 1.765±0.39 | 512 | >2048 |
| 183 | 0.333±0.08 | 1.372±0.04 | 0.845±0.04 | 0.855±0.53 | 0.928±0.3 | 512 | >2048 |
Abbreviations: CIP, ciprofloxacin; Sub-MIC, sub-minimal inhibitory concentration; MIC-b, minimum inhibitory concentration of biofilm; MBIC, minimum biofilm inhibition concentration.