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. 2020 Aug 11;13:7973–7984. doi: 10.2147/OTT.S264108

Table 1.

Expression of USP8 and HER-2 and Patient Characteristics

Characteristic No. USP8 P value HER-3 P value
High Expression Low Expression High Expression Low Expression
Gender 0.862 0.520
 Male 75 19 56 24 51
 Female 13 3 10 3 10
Age (yr) 0.218 0.682
 <60 42 8 34 12 30
 ≥60 46 14 32 15 31
Tumor size (cm) 0.177 0.991
 <3 27 4 22 8 18
 ≥3 61 18 44 19 34
Location 0.805 0.958
 AEG 46 11 35 14 32
 Others 42 11 31 13 29
Differentiation 0.665 0.810
 Well/Moderate 21 6 15 6 15
 Poor 67 16 51 21 46
Lauren type 0.771 0.464
 Intestinal 41 11 30 11 30
 Diffuse 47 11 36 16 31
Nerve invasion 0.065 0.016
 Yes 45 15 30 19 26
 No 43 7 36 8 35
Vascular tumor emboli 0.268 0.078
 Yes 43 13 30 17 26
 No 45 9 36 10 35
T stage 0.295 0.112
 T1+T2 19 3 16 3 16
 T3+T4 69 19 50 24 45
N stage 0.006 0.001
 N0 29 2 27 2 27
 N13 59 20 39 25 34
pTNM stage 0.004 0.021
 I+II 39 4 35 7 32
 III 49 18 31 20 29

Note: P values were calculated by the chi-square test.

Abbreviations: AEG, adenocarcinomas of the esophagogastric junction; T, tumor; N, node; pTNM, pathological tumour node metastases.