(A) Manual synthesis: (i): [18F]potassium fluoride, Kryptofix222, potassium carbonate, dimethyl sulfoxide, 95 °C, 10 min. (B) Automated synthesis: (i):[18F]potassium fluoride, Kryptofix222, potassium carbonate, dimethyl sulfoxide, r.t., 10 min; (ii): 2M potassium hydroxide in H2O, 105 °C, 10 min; (iii): ethyl tosylate, potassium carbonate, dimethylformamide, 110 °C, 10 min.