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. Author manuscript; available in PMC: 2021 Aug 14.
Published in final edited form as: ACS Infect Dis. 2020 Jul 14;6(8):2169–2180. doi: 10.1021/acsinfecdis.0c00258

Table 3.

Antimicrobial activity of 1, 2, 5, 9, 15 and 19 against VanB and S. aureus strains, MIC (μg/mL).

Compound VanB E. faecalis Sensitive S. aureus MRSA S. aureus
ATCC 51299 ATCC 25923 ATCC 43300
vancomycin (1) 8 0.5 0.5
G3-vancomycin (5) 8 0.25 0.12
GBn-vancomycin (9) 8 0.25 0.12
CBP-vancomycin (2) 0.08 0.08 0.08
G3-CBP-vancomycin (15) 0.04 0.04 0.02
GBn-CBP-vancomycin (19) 0.04 0.04 0.02