Table 3.
Multivariable regression: mixed models predicting median ppFEV1, by tobacco smoke exposure (N=65,581 person-years)
| Median ppFEV1 |
||||
|---|---|---|---|---|
| Smoke-exposed | Unexposed | |||
| β (95% CI) | p-value | β (95% CI) | p-value | |
| Intercept (ppFEV1 at age 6) | 92.8 (91.1, 94.3) | <0.001 | 96.8 (96.0, 97.6) | <0.001 |
| Household income, each $10,000 | 0.31 (0.17, 0.46) | <0.001 | 0.17 (0.07, 0.27) | <0.001 |
| Paternal education | ||||
| Less than high school | −3.49 (−6.28, −0.71) | 0.014 | −5.71 (−7.88, −3.54) | <0.001 |
| High school | −2.48 (−4.08, −0.88) | 0.003 | −2.40 (−3.45, −1.36) | <0.001 |
| Some college | −0.38 (−2.28, 1.52) | 0.694 | −1.68 (−2.75, −0.61) | 0.003 |
| College degree | 1.00 (reference category) | 1.00 (reference category) | ||
| Health insurance | ||||
| Private only | 1.00 (reference category) | 1.00 (reference category) | ||
| Public only | −0.63 (−1.12, −0.13) | 0.013 | −0.21 (−0.54, 0.11) | 0.202 |
| Both private and public | −0.33 (−0.88, 0.23) | 0.250 | 0.08 (−0.26, 0.42) | 0.641 |
| None/other | −1.38 (−2.71, −0.06) | 0.041 | −0.04 (−0.93, 0.86) | 0.938 |
| Annual rate of change | 0.30 (0.09, 0.52) | 0.005 | 0.17 (0.04, 0.30) | 0.012 |
| Annual rate of change, squared | −0.14 (−0.16, −0.12) | <0.001 | −0.12 (−0.13, −0.11) | <0.001 |
All models adjusted for sex, race/ethnicity, household size, BMI, genotype, newborn screening, hospitalizations, pulmonary exacerbations, modulator use, P. aeruginosa, and B. cepacia.
Boldface indicates statistical significance: p<0.05, two-tailed tests.