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. Author manuscript; available in PMC: 2021 Aug 10.
Published in final edited form as: J Control Release. 2020 May 26;324:450–459. doi: 10.1016/j.jconrel.2020.05.040

Figure 4.

Figure 4.

Reduced changes in fMRI BOLD signal in response to hind paw stimulation following FUSBBB opening. A) Axial views of the rat cortex showing regions for left and right hind paw somatosensory cortex and an example of FUS-BBB opening targeted to the right hind paw somatosensory cortex. B) Group average results showing significantly reduced BOLD response to hind paw stimulation in the right somatosensory cortex targeted for BBB opening. C) Similar results from ASL imaging showing significantly reduced CBF response to hind paw stimulation.