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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Trends Cogn Sci. 2020 Jun 27;24(9):734–746. doi: 10.1016/j.tics.2020.06.003

Figure 1. Spontaneous (intrinsic, non-evoked) activity is observed in the brain at multiple spatio-temporal scales.

Figure 1.

Top: Spontaneous action potentials recorded from a neuron bathed in physiological saline (from [110]). Bottom: Functional connectivity measured using resting state fMRI (from [111]). Anatomically separate brain regions [insula (purple), and anterior cingulate cortex, light blue] that form known functional networks [salience/mid-cingulo-insular network [44,112]] exhibit spontaneous, low-frequency correlations even in the absence of cognitive task performance.