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(A) and (B) MALDI-MS methylation inhibition assay compound 3 (n=2). (A) MALDI-MS results of MALDI-MS methylation inhibition assay for compound 3; (B) Quantification of methylation progression of GPKRIA by NTMT1 with 3 at 20 min. (C) Selectivity evaluation of compound 3 (n=2).
