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. 2020 Aug 10;13:7517–7530. doi: 10.2147/OTT.S256464

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© 2020 Liu and Meng.

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LINC00662 knockdown inhibited tumorigenesis of osteosarcoma (OS) cells. (A) The expression of LINC00662 in HOS, MG63, SJSA-1, U2OS and hFOB cells was detected by qRT-PCR. **P < 0.01 vs hFOB; (B) The expression of LINC00662 in MG63 and U2OS cells was detected by qRT-PCR. **P < 0.01 vs sh-NC; (C) The proliferation of MG63 and U2OS cells was detected by MTT assay. *P < 0.05, **P < 0.01 vs sh-NC; (D) The wound healing rate of MG63 and U2OS cells was detected by wound healing assay. **P < 0.01 vs sh-NC; (E) The invasion rate of MG63 and U2OS cells was detected by transwell assay. **P < 0.01 vs sh-NC; (F) Tumor in nude mice. (G) Tumor volume and tumor weight. *P < 0.05, **P < 0.01 vs sh-NC.