FIGURE 2.

Recombinant human thrombomodulin (rhTM) attenuated LPS‐induced endothelial glycocalyx injury. (a) Representative image of Western blotting of syndecan‐1 in the lungs of sham and saline‐ or rhTM‐treated mice after LPS injection. (b) Densitometry showing relative levels of syndecan‐1 (n = 5 per group). ^* P < .05, significantly different from sham or LPS+rhTM. (c) Lectin, a glycocalyx‐binding glycoprotein, stained by wheat germ agglutinin (WGA). Bars: 50 μm. (d) WGA intensity of saline‐ and rhTM‐injected mouse lungs with and without LPS administration (n = 6 each). ^* P < .05, significantly different from sham mice. ⁺ P < .05 significantly different from saline+LPS group