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. 2020 Jul 14;177(17):4021–4033. doi: 10.1111/bph.15153

FIGURE 6.

FIGURE 6

Immunohistochemical analysis of Ki67 and heparan sulfate 6‐O‐sulfotransferase 1 (HS6ST1). (a) Immunohistochemical analysis of Ki67 in the lungs of sham mice and saline‐injected and recombinant human thrombomodulin (rhTM)‐treated mice after LPS administration. Arrows indicate Ki67‐positive cells. (b) Graph showing Ki67‐positive cell numbers (n = 6 each). * P < .05, significantly different from sham mice. (c) Immunohistochemical analysis of HS6ST1 in the lungs of sham mice and saline‐injected and rhTM‐treated mice after LPS administration. Arrows indicate HS6ST1‐positive endothelial cells. (d) Graph showing HS6ST1‐positive cell numbers (n = 6 each). * P < .05, significantly different from sham mice. (e) Double immunofluorescence analysis of HS6ST1 and CD31. The magnified image is the expanded view of the white‐boxed area in the merged image. HPF, high‐power field