Fig. 6.

Lasso regression analysis of 19 m⁶A regulators to identify the prognostic model of three-m⁶A-regulator gene signature (2 = KIAA1429, 9 = METTL3, and 17 = IGF2BP1) between log(lambda) value from − 4 to − 3. a, b Lasso regression complexity was controlled by lambda using the glmnet R package (1 = RBM15; 2 = KIAA1429; 3 = ZC3H13; 4 = HNRNPC; 5 = YTHDC2; 6 = METTL14; 7 = YTHDC1; 8 = WTAP; 9 = METTL3; 10 = FTO; 11 = ALKBH5; 12 = YTHDF1; 13 = YTHDF2; 14 = RBM15B; 15 = YTHDF3; 16 = HNRNPA2B1; 17 = IGF2BP1; 18 = IGF2BP2; 19 = IGF2BP3). c Overall survival analysis between the high-risk score and low-risk score group derived from lasso regression