Fig. 1.
Schematic of reaction-diffusion-advection (RAD) model. External or internal stress causes strain. The membrane receptors that can bind to arbitrary molecules A are denoted R in the unbound form and AR in the bound form. The binding process is . A is free to diffuse in any direction, whereas R is limited to diffuse along the membrane plane, with the diffusion coefficients of DA and DR, respectively. The concentration of molecules A varies due to diffusion and reaction but also varies due to advection (shown by velocity vector field vA). Advection could be a consequence of strain or cell contraction (e.g., in CMs)