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. 2020 Aug 15;20:395. doi: 10.1186/s12935-020-01479-2

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — miR-502-5p overexpression suppresses gastric cancer cells migration and invasion. a The wound healing analysis showed that miR-502-5p overexpression inhibited the migration ability of gastric cancer cells SGC7901 and MGC803. **P < 0.01, ***P < 0.001. The representative images were shown on top. Magnification ×200. b Transwell assays were performed to determine the migration abilities of SGC7901 and MGC803 cells transfected with miR-502-5p or miR-NC. The number of cells migrating from the transwell membrane was quantified after incubation for 24 h. Magnification ×200. Data are representative of three similar experiments. *P < 0.05, **P < 0.01. c The invasive ability was investigated by transwell-matrigel assay. The number of cells invading through the transwell membrane coated with matrigel was quantified after incubation for 24 h. Magnification ×200. Data are representative of three similar experiments. *P < 0.05, **P < 0.01