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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Food Chem Toxicol. 2019 Sep 20;134:110819. doi: 10.1016/j.fct.2019.110819

Fig. 2.

Fig. 2.

RISK21. Estimates of exposure from Table 1, and the most sensitive NOEL/NOAEL value from Table 2 were used to develop a RISK21 plot using the RISK21 webtool. The ExpoCast estimates of exposure are used as the lower estimate of exposure for both DBTC and SPO, and the upper estimates of exposure are the CEDI value for SPO and the SHEDS-HT value for DBTC. Estimates of toxicity (a NOEL of 0.5 mg/kgbw/d for SPO and a NOAEL of 0.025mg/kgbw/d for DBTC) were plotted as point estimates with an uncertainty factor of 100 to define the reference dose or tolerable daily intake established limit for each compound. The top of the colored boxes per chemical denote the reference dose or the tolerable daily intake, and the bottom of the box is the dose given to the animal used to determine that limit.