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. 2020 Jul 9;39(16):e105057. doi: 10.15252/embj.2020105057

Figure 3. Cell‐type specificity, modulation, and characteristics of the AM‐EV activity against influenza.

Figure 3

  1. EVs isolated from MH‐S AMs and A549 AECs were co‐incubated in parallel with Luc‐WSN/33 (MOI = 0.5) in MDCK‐SIAT1 cells. Data represent mean luminescence AUC from individual wells normalized to the mean of the corresponding control condition from 3 independent experiments.
  2. EVs isolated from MH‐S cells treated with increasing concentrations of CSE were co‐incubated with Luc‐WSN/33 in MLE‐12 cells. Data represent mean luminescence at 12 h post‐infection from individual wells normalized to the mean of untreated AM‐EVs from 3 independent experiments per condition.
Data information: Error bars = SD. One‐way ANOVA (A, B) (*P value of < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001).Source data are available online for this figure.