The onset of symptoms after 20 weeks’ gestation with remission by 6–12 weeks postpartum*
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Mild pre-eclampsia: |
• Hypertension (Systolic Blood Pressure(SBP) ≥ 140 mmHg or Diastolic Blood Pressure(DBP) ≥ 90 mmHg), may be superimposed on chronic hypertension |
• Proteinuria (proteinuria ≥300 mg/24 h, or significant increase from baseline) |
Severe pre-eclampsia if one or more of the following: |
• Sustained Systolic Blood Pressure(SBP) ≥ 160 mmHg or Diastolic Blood Pressure(DPB) ≥ 110 mmHg (measured twice, at least 6 h apart) |
• Evidence of other end-organ damage |
• Deteriorating renal function including nephrotic range proteinuria ≥3 g/24 h or 3+ on urine dipstick or sudden oliguria, especially with elevated creatinine†
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• Central Nervous System(CNS) disturbance (altered vision, headache) |
• Pulmonary edema (3% of patients) |
• Liver dysfunction |
• Epigastric/right upper quadrant pain (stretching of hepatic capsule) |
• Thrombocytopenia (15–30% of patients) |
• HELLP syndrome is characterized by Hemolysis Elevated Liver enzymes and Low platelet count which may occur without proteinuria. |
• Evidence of fetal compromise (Intrauterine Growth Restriction-IUGR, oligohydramnios, non-reasoning fetal testing) |