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. 2020 Aug 14;3:438. doi: 10.1038/s42003-020-01174-y

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Fig. 6 — The number below each agent indicates the number of unique mutants sequenced, while the number in each box represents the percent contribution of each signature to the mutation profile of each tested agent. Only those signatures that passed the criteria for inclusion (i.e., detected by both deconstructSigs and MutationalPatterns; at least 20% contribution by both methods; and cosine similarity >0.5 with the mutation profile) are shown. DS = deconstructSigs; MP = MutationalPatterns.