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. 2020 Aug 14;11(8):626. doi: 10.1038/s41419-020-02751-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Serum triglyceride (a), serum total cholesterol (b), serum LDL (c), and serum HDL (d) levels in mice were detected by a biochemical analyzer. Serum oxLDL (e) and testicular oxLDL (f) levels were measured by ELISA. *P < 0.05, **P <0.01, compared with SD-fed mice. (g) Immunohistochemical staining indicated that oxLDL accumulated in the testicles in SD- and HFD-fed mice, and the arrows show sites of positive expression (n = 8 per group; scale bar, 20 μm). Transmission electron microscopy showing the ultrastructural characteristics of mitochondria of Leydig cells in SD- and HFD-fed mice. The arrows show the absence of mitochondrial cristae (n = 8 per group; scale bar, 0.5 μm).