Fig. 7. CD36 expression is indispensable for decreased lipid accumulation induced by deletion of UCHL1.

Macrophages were pretreated with anti-CD36 or IgG antibody for 1 h, followed by exposed to either LDN57444 or UCHL1 siRNA for the indicated time. a, c OxLDL treatment for the last 24 h and macrophages were stained with oil red O. e, f Dil-oxLDL was used to treat cells for the additional 6 h, followed by confocal microscopy. The represented images were shown and from three independent experiments. b, d Quantitative analysis of Oil Red O-positive cells and g fluorescence intensity were present.