Table 1.
Diabetes (n = 166) | No Diabetes (n = 189) | p value | |
---|---|---|---|
Age (mean ± SD) | 66.42 ± 12.67 | 66.03 ± 15.46 | 0.797 |
Female gender n (%) | 80 (48) | 101 (53) | 0.340 |
Ethnicity n (%) | 0.515 | ||
African-American | 118 (71) | 134 (71) | |
Caucasian | 10 (6) | 17 (9) | |
Hispanic | 21 (13) | 17 (9) | |
Other | 17 (10) | 21 (11) | |
Comorbidities | |||
BMI (mean ± SD) | 31.09 ± 8.53 | 28.53 ± 9.43 | 0.009 |
COPD | 22 (13) | 23 (12) | 0.873 |
Asthma | 11 (7) | 16 (9) | 0.553 |
Heart failure | 40 (24) | 20 (11) | 0.001 |
Atrial fibrillation | 15 (9) | 24 (13) | 0.310 |
Liver cirrhosis | 5 (3) | 5 (3) | 1.000 |
Chronic kidney disease | 42 (25) | 23 (12) | 0.002 |
End-stage renal disease on dialysis | 27 (16) | 14 (7) | 0.012 |
Coronary artery disease | 45 (27) | 32 (17) | 0.028 |
Hypertension | 151 (91) | 121 (64) | < 0.0001 |
HIV | 3 (2) | 4 (2) | 1.000 |
Clinical and laboratory parameters (mean ± SD) | |||
FiO2% requirement on admission | 28 (21–44) | 27 (21–40) | 0.324 |
Serum ferritin on admission (ng/mL) | 917 (414–1922) | 802 (262–1721) | 0.187 |
Peak ferritin (ng/mL) | 1375 (594–3605) | 1128 (354–2940) | 0.074 |
D-dimer on admission (ng/mL) | 2035 (1062–3490) | 1605 (820–3095) | 0.187 |
Peak D-dimer (ng/mL) | 3710 (1633–8375) | 2940 (1315–7923) | 0.302 |
CRP on admission (mg/L) | 143 (65–230) | 125 (50–192) | 0.091 |
Peak CRP (mg/L) | 184 (111–258) | 142 (65–229) | 0.012 |
Procalcitonin (ng/mL) | 0.28 (0.10–1.13) | 0.18 (0.08–0.68) | 0.080 |
Peak procalcitonin (ng/mL) | 0.46 (0.11–2.79) | 0.28 (0.10–1.19) | 0.065 |
LDH on admission (IU/L) | 422 (310–573) | 397 (257–537) | 0.146 |
Peak LDH (IU/L) | 560 (384–758) | 499 (324–655) | 0.017 |
COVID-19 treatment | |||
Hydroxychloroquine | 100 (60) | 116 (61) | 0.828 |
Steroids | 58 (35) | 45 (24) | 0.026 |
Tocilizumab | 21 (13) | 22 (12) | 0.871 |
Clinical outcomes | |||
Median days of hospitalization | 7 (4–14) | 7 (4–12) | 0.831 |
Inpatient death | 45 (27) | 35 (19) | 0.053 |
Need for RRT/HD | 35 (21) | 21 (11) | 0.013 |
Need for vasopressors | 47 (28) | 34 (18) | 0.023 |
Need for intubation | 48 (29) | 41 (22) | 0.141 |