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. 2020 Aug 14;11(8):632. doi: 10.1038/s41419-020-02902-2

Fig. 8. HHT repressed β-catenin and EMT-related molecules through EphB4 suppression.

Fig. 8

a Protein expression of β-catenin, p-β-catenin, E-cadherin, Snail, MMP2, and MMP9 in HepG2 cells treated with either: HHT (20 nM), NVP-BHG-712 (1 μM), or the combination of both. b Protein expression of EphB4, β-catenin, p-β-catenin, E-cadherin, Snail, MMP2, and MMP9 in HepG2 cells treated with HHT (20 nM) for the indicated duration. c Protein expression of EphB4, E-cadherin, Snail, MMP2, and MMP9 in HepG2 cells treated with either: vehicle, TGF-β, TGF-β + HHT, TGF-β + NVP-BHG712, or TGF-β + HHT + NVP-BHG712. d Schematic diagram of HHT inhibited the migration of HCC.