Table 1. Electrophysiological Activity of αKTx5 Toxin Family Reported against the SK2 and SK3 Channelsa.
EC50 nM |
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---|---|---|---|---|
Toxin | SK2 | SK3 | % Identity | Reference |
Tamapin | 0.024 | 1.7 | 100 | (11) |
Scyllatoxin | 0.29 | 1.1 | 77 | (13) |
BmP05 | 3.8 | 74 | (14) | |
Apamin | 0.027 | 1.1 | NA | (15) |
Apamin is included as blocker reference of these channels. Identity column is with respect to r-tam.