Table 5. Molecular properties of compounds 1 through 5.

Properties	1	2	3	4	5
mlog P	2.43	2.45	1.72	3.14	3.77
tPSA (Å2)	66.84	92.18	92.42	79.29	86.62
N atoms	20	21	16	21	22
MW	299.39	307.38	244.32	306.39	321.40
HBA	5	6	5	5	5
HBD	1	2	4	2	3
N violations	0	0	0	0	0
NRB	3	4	3	4	4
Molar volume (Å3)	268.14	265.50	213.69	269.66	281.83