Table 2.
Reported contra-indications for ECPR per study
| Authors | CPR duration in minutes | Non-witnessed arrest | Severe comorbidity precluding ICU treatment | Advanced age (years) | Terminal cancer | Advanced CAD/heart failure | Non pre-selected patient categories* | Previous severe or irreversible brain damage | Liver cirrhosis | Renal failure | Uncontrollable sepsis | Uncontrollable bleeding/trauma | Irreversible (multi) organ failure | Arrest of septic origin | Coagulation disorder | BMI > 40 | Weight < 30 kg | Aortic dissection | Extensive peripheral artery disease | Bedridden, care-dependant | At the discretion of the CPR team |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avalli et al. | < 30 | > 75 | x | X | x | x | x | ||||||||||||||
| Bednarcyzk et al | < 15 | x | x | x | x | x | x | x | x | x | x | ||||||||||
| Blumenstein et al. | x | x | x | X | x | x | x | x | |||||||||||||
| Chen et al. | < 10 | x | > 75 | x | x | x | x | x | |||||||||||||
| Dennis et al. | x | ||||||||||||||||||||
| Ellouze et al. | < 30 | x | > 75 | x | x | x | |||||||||||||||
| Fagnoul et al. | < 10 | x | x | > 65 | x | X | x | x | x | x | x | ||||||||||
| Lazzeri et al. | < 30 | > 75 | x | x | x | x | x | ||||||||||||||
| Liu et al. | < 10 | x | x | x | x | x | |||||||||||||||
| Jung et al. | > 74 | x | x | ||||||||||||||||||
| Lee et al. | x | ||||||||||||||||||||
| Lin et al. | x | x | X | x | x | ||||||||||||||||
| Mazzeffi et al. | < 10 | x | x | ||||||||||||||||||
| Peigh et al. | > 70 | x | X | x | x | x | |||||||||||||||
| Pozzi et al. | < 20 | x | x | X | x | x | |||||||||||||||
| Shin et al. | > 80 | x | x | x | x | x | |||||||||||||||
| Spangenberg et al. | < 20 | x | |||||||||||||||||||
| Stub et al. | > 65 | x | x | x | x | X | |||||||||||||||
| Wang et al. | < 10 | x | x | > 80 | x | x | x | x | x |
*Some studies selected pre-specified groups based on cardiac arrest aetiology. Liu: acute myocardial infarction; Mazeffi: post-cardiac surgery; Chen/Spangenberg: cardiac origin; Stub: cardiac origin with ventricular fibrillation; Jung: cardiac origin or pulmonary embolism