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. Author manuscript; available in PMC: 2021 Aug 21.
Published in final edited form as: Nanoscale. 2020 Jun 17;12(31):16451–16461. doi: 10.1039/d0nr03226c

Table. 1.

IC50 of ANS–TAT–AuNPs and 6-MP–TAT–AuNPs after 24 h incubation and DRI of MCF-7/ADR cells.

Samples IC50/μM *
DRI (W/O VRP)* DRI (W VRP)*
MCF-7 MCF-7/ADR MCF-7/ADR (W VRP)*

ANS–TAT–AuNPs4.1nm 9.0 ± 0.7 45.7 ± 3.5 19.5 ± 4.7 5.1 2.2
6-MP–TAT–AuNPs4.1nm 7.4 ± 2.3 44.4 ± 6.5 20.2 ± 1.6 6.0 2.7
ANS–TAT–AuNPs5.4nm 10.3 ± 1.2 25.2 ± 3.2 25.9 ± 4.2 2.4 2.5
6-MP–TAT–AuNPs5.4nm 11.2 ± 1.5 20.5 ± 0.2 20.1 ± 2.2 1.8 1.8
*

calculated based on the concentration of ANS or 6-MP. W VRP: pre-treated with verapamil at 10 μM for 1 h; W/O VRP: without verapamil pre-treatment.