Table 3.
Standard dose prophylaxis Hospitalization in the medical ward |
||
---|---|---|
glomerular filtration rate* (ml/mn) | Weight 50-99 kg | Weight ≥100 kg |
≥30 | Enoxaparin 40 mg/d Nadroparin 2 850 UI/d Tinzaparin 4500 UI/d Fondaparinux 2.5 mg/d |
Enoxaparin 60 mg/d Nadroparin 5700 UI/d Fondaparinux 5 mg/d |
20-30 | Enoxaparin 20 mg/d Tinzaparin 3500 UI/d |
UFH 5000 UI x 3 /d Targeted anti-factor Xa level: 0.50-0.70 IU/mL |
<20 | UFH 5000 UI x 2 /d Targeted anti-factor Xa level: 0.30-0.50 IU/mL |
|
Hospitalization in ICU Enhanced dose prophylaxis |
||
≥30 | Enoxaparin 40 mg x 2/d Nadroparin 2850 x 2/d |
Enoxaparin 60 mg x 2/d Nadroparin 5700 UI x 2/d |
<30 | UFH 5000 UI x 3 /d or 15.000 UI / 24 h continuous IV |
UFH10 000 UI x 2 /d or 20.000 UI / 24 h continuous IV |
UFH: unfractioned heparin; UI: international units; IV: intra-venous; d: day; ICU: intensive care unit; kg: kilogram; * Cockroft.