Table 2.

Demographics of patients with leg ulcer and those without leg ulcer

	Leg ulcer		*p value
	Yes (N = 68)	No (N = 591)
Country of residence	N (%)	N (%)
USA	6 (2.4%)	249 (97.6%)	<0.001**
**Ghana (87%of leg ulcer cases)	59 (18.6%)	259 (81.4%)
Italy	3 (3.5%)	83 (96.5%)
Genotype
***SS	62 (13.0)	412 (87.0)	<0.001***
SC	3 (2.3)	129 (97.7)
SBeta Thal Zero	3 (13.0)	20 (87.0)
SBeta Thal Plus	0 (0)	30 (100)
Sex
Male	42 (13.9)	261 (6.1)	0.010
Female	26 (7.4)	330 (92.6)
Age category
Pediatrics (< 18 years old)	7 (2.9)	233(97.1)	< 0.001
Adults (≥ 18 years old)	61(14.5)	358 (85.5)

^*p value, one way Anova for each category;

^**p value, Ghana vs. other countries;

^***p value, SS genotype vs. other genotypes;

^*p value < 0.05 was significant