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. 2020 Aug 10;11:1834. doi: 10.3389/fmicb.2020.01834

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Copyright © 2020 Petito, de Curcio, Pereira, Bailão, Paccez, Tristão, de Morais, de Souza, de Castro Moreira Santos, Fontes, Ricart and de Almeida Soares.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Metabolic pathways regulated in P. brasiliensis in response to in vitro copper deprivation. Heat map showing increased quantity of proteins from beta oxidation, TCA and glyoxylate cycle in copper deprived P. brasiliensis yeast cells. Colors on the heat map indicate differential accumulation; red increased and green decreased. The heat map was constructed by GraphPad Prism software. Copper deprivation (50 μM BCS) and control (10 μM of CuSO₄).