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. Author manuscript; available in PMC: 2020 Aug 17.
Published in final edited form as: Cell Rep. 2020 Jul 28;32(4):107962. doi: 10.1016/j.celrep.2020.107962

Figure 3. Transcriptional Characterization of hiPSC-Derived Human Neurons at 7 MPT.

Figure 3.

(A) Experimental design for collecting snRNA-seq data from transplanted human neurons. E3KI mice (iE3/3 transplants, N = 6; E4/4 transplants, N = 6). E4KI mice (iE3/3 transplants, N = 6; E4/4 transplants, N = 5).

(B) Feature plots of classical panneuronal (RBFOX3 and SYN1), excitatory neuron (NEUROD6 and SLC17A7), and inhibitory neuron (DLX1 and GAD1) markers.

(C) t-distributed stochastic neighbor embedding (tSNE) clustering of transplanted hiPSC-derived neurons.