FIG 2.

Adjusted associations of pathogenic mutations in DNA repair genes with rates of subsequent neoplasms by treatment exposures. (A) The associations of mutations in homologous recombination (HR) genes and the rate of subsequent female breast cancer. (B) The association of mutations in HR genes and the rate of subsequent sarcoma. (C) The association of mutations in nucleotide excision repair (NER) genes and the rate of subsequent thyroid cancer. The relative rate is denoted as not applicable (NA) if the model did not converge. RT, radiotherapy.