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. 2020 Aug 12;7(1):e000606. doi: 10.1136/bmjresp-2020-000606

Table 4.

Side effects associated with the multidrug-resistant tuberculosis treatment

Side effects (n=90) Offending drugs n (%)
Arthralgia Levofloxacin, pyrazinamide 63 (70)
Hypothyroidism Ethambutol 50 (55.6)
Gastrointestinal symptoms Ethambutol, ethionamide 41 (45.6)
Dizziness/vertigo Kanamycin, levofloxacin 20 (22.2)
Hearing loss Kanamycin 6 (6.7)
Clinical signs of hepatotoxicity Pyrazinamide, ethionamide 2 (2.2)
Alopecia 1 (1.1)
Central nervous system
 Sleep disturbances/minor mood Cycloserine, levofloxacin 15 (16.7)
 Depression Cycloserine 5 (5.6)
 Psychosis Cycloserine 4 (4.4)
 Suicidal thoughts Cycloserine, levofloxacin 2 (2.2)