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. 2020 Aug 13;8(2):e000631. doi: 10.1136/jitc-2020-000631

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

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Waterfall plot of the response of patients with gastrointestinal cancers to ICIs. (A) Waterfall plot showing the candidate biomarkers in the discovery cohort. The Y-axis represents the percentage change in the summed longest diameters of the target lesions from baseline. (B) Waterfall plot showing the results for the validation cohort. dMMR, deficient mismatch repair; ICIs, immune checkpoint inhibitors; IO, immune oncology; MSI, microsatellite instability; MSS, microsatellite stability; PD-L1, programmed death ligand 1; pMMR, proficient mismatch repair; TMB, tumor mutational burden.