Table 2.

A: MR acquisition parameters for Phase 1 (n=54)

Sequence type	Slice orientation	TR (ms)	TE (ms)	Flip angle (°)	Acquisition matrix:	Reconstructed resolution (mm)	Other parameters	Acquisition duration (min:s)
A: MR acquisition parameters for phase 1 (n=54)
3D-T1	Coronal	~7	~2.5	8	256×256	0.94×0.94×1.0	TI=650 ms	5:03
FLAIR	Axial	9000	148	90	256×256	0.94×0.94×3.0	TI=2250 ms	4:50
rs-fMRI	Axial	2000	30	70	64×64	3.75×3.75×3.8	200 Volumes	5:10
DWI	Axial	9000	~80	90	80×80	0.94×0.94×3.0	b=1000 s/mm2; 31 directions	6:01
qT118	Axial	15 000	~24	40	160×160	1.0×1.0×4.0	Eight echoes; B1 map included	8:09
qT2	Coronal	3000	~8 to 128	90	256×128	0.94×0.94×4.0	16 Echoes; echo spacing=8 ms	9:48
QSM19	Axial	30	~3 to 28	20	192×192	1.0×1.0×1.0	Eight echoes; echo spacing=3.4 ms	4:13
pcASL	Axial	4899	~11	111	512×10	1.88×1.88×5.0	Post label delay=2025 ms; NEX=1	6:55
B: MR acquisition parameters for Phase 2 (n=271)
3D-T1	Sagittal	~7	~2.5	8	256×256	0.94×0.94×1.0	TI=650 ms	5:44
FLAIR	Axial	9000	148	90	256×256	0.94×0.94×3.0	TI=2250 ms	4:50
rs-fMRI	Axial	2000	30	70	64×64	3.75×3.75×3.8	200 Volumes	5:10
DWI	Axial	9000	~80	90	80×80	0.94×0.94×3.0	b=1000 s/mm2; 31 directions	6:01
qT120	Axial	15 000	~24	40	160×160	1.0×1.0×4.0	Eight echoes; variable TI	5:35
qT2	Axial	3000	~8 to 128	90	256×128	0.94×0.94×4.0	16 Echoes; echo spacing=8 ms	9:48
QSM19	Axial	30	~3 to 28	20	192×192	1.0×1.0×1.0	Eight echoes; echo spacing=3.4 ms	3:58
pcASL	Axial	4899	~11	111	512×8	1.79×1.79×3.5	Post label delay=2025 ms; NEX=3	4:45

T1, spin–lattice relaxation time constant.

T2, spin–spin relaxation time constant.

TI, inversion time.

DTI, diffusion tensor imaging; DWI, diffusion-weighted imaging; FLAIR, fluid attenuated inversion recovery; IR, inversion recovery; MR, magnetic resonance; NEX, number of excitations; pcASL, pseudo-continuous arterial spin labelling; QSM, quantitative susceptibility mapping; rs-fMRI, resting state functional MRI.