Table 2.
Iron concentrations in striatum, spleen, and liver.
| Tissues | WT (n=10) | MOR KO (n=11) | Sex X Genotype | Sex | Genotype | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Striatum | 23.87 ± 4.70 | 23.16 ± 6.46 | F1,17=0.59 | F1,18=5.10 | F1,18=0.10 | ||||||
| p=0.45 | p=0.04* | p=0.76 | |||||||||
| Spleen | 739.20 ± 467.63 | 1118.70 ± 336.62 | F1,17=0.01 | F1,18=1.00 | F1,18=4.38 | ||||||
| p=0.91 | p=0.33 | p=0.05* | |||||||||
| Female | Male | Sex X Genotype | Sex | Genotype | |||||||
| WT (n=5) | MOR KO (n=4) | F1,7 | p | WT (n=5) | MOR KO (n=6) | F1,9 | p | ||||
| Liver | 178.75±34.46 | 197.46±12.66 | 1.04 | 0.53 | 98.16±45.37 | 154.34±58.89 | 3.03 | 0.05* | F1,16=0.89 | F1,17=9.92 | F1,17=4.01 |
| p=0.36 | p<0.01** | p=0.06 | |||||||||
The values of each parameter are presented in means ± SDs and p-values for interactions (Sex X Genotype) were calculated by mixed model ANOVA. The p-values for sex and genotype were calculated by mixed model ANOVA with the interaction removed. The p-values for the genotype of each sex were calculated by mixed model ANOVA using BY commend.
*
p≤0.05;
**
p<0.01. WT, wild-type mice. MOR KO, mu opioid receptor knockout mice.