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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: J Neurosci Res. 2020 May 19;98(8):1532–1548. doi: 10.1002/jnr.24637

Table 4.

Wheel-running activity.

Time WT (n=5) MOR KO (n=5) Period X Genotype p for Period p for Genotype
Estimate SE 95% CI Estimate SE 95% CI Z
Light phase 0 0 0 1.39 0.61 0.19 and 2.59 2.28 0.07 0.11 0.02*
Dark phase 0 0 0 −0.23 0.24 −0.70 and 0.25 −0.94 0.83 0.09 0.35

The p-values for interactions were calculated by GENMOD with a negative binomial distribution with period and genotype as factors. The parameters and p-values for period and genotype were calculated by GENMOD with a negative binomial distribution with the interaction removed.

*

p≤0.05;

**

p<0.01. WT, wild-type mice. MOR KO, mu opioid receptor knockout mice. SE, standard error. 95% CI, 95% confidence interval.