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. 2020 Aug 17;14(8):e0008381. doi: 10.1371/journal.pntd.0008381

Table 4. Clinical symptoms associated with pathogens.

Complaints of symptoms prior to hospitalization collected during enrollment. Bolded value with asterisk indicates the value is significantly different from patients without the indicated pathogen. Clinical symptoms were compared for patients with different infectious etiologies as described above. All tests of statistical significance were two-tailed, and significance was defined as p<0.05.

Symptom None
(N = 107)
B. pseudomallei
(N = 23)
Dengue virus
(N = 21)
O. tsutsugamushi
(N = 16)
SFG
(N = 12)
Leptospira spp.
(N = 10)
K. pneumoniae
(N = 8)
AFB
(N = 7)
E. coli
(N = 5)
Fever 95 (89%) 21 (91%) 20 (95%) 15 (93.75%) 11 (92%) 9 (90%) 6 (75%) 7 (100%) 5 (100%)
Rigors 60 (56%)* 19 (83%) 17 (81%) 13
(81.25%)
9 (75%) 8 (80%) 4 (50%) 7 (100%) 4 (80%)
Sweat 72 (67%) 17 (74%) 14 (67%) 13 (81.25%) 8 (67%) 8 (80%) 6 (75%) 3 (43%) 3 (60%)
Dizzy 37 (35%)* 13 (57%) 9 (43%) 8 (50%) 5 (42%) 5 (50%) 5 (63%) 4 (57%) 3 (60%)
Headache 68 (64%) 15 (65%) 14 (67%) 12 (75%) 8 (67%) 4 (40%) 6 (75%) 3 (43%) 3 (60%)
Retro-orbital pain 23 (22%) 7 (30%) 6 (29%) 8 (55%)* 2 (17%) 1 (10%) 3 (38%) 1 (14%) 2 (40%)
Blurred vision 41 (38%) 8 (35%) 10 (48%) 13 (81.25%)* 5 (42%) 5 (50%) 2 (25%) 3 (43%) 2 (40%)
Hearing 26 (24%) 4 (17%) 6 (29%) 6 (37.5%) 5 (42%) 2 (20%) 3 (38%) 2 (29%) 1 (20%)
Confusion 20 (19%) 3 (13%) 4 (19%) 4 (25%) 2 (17%) 4 (40%)* 0 0 0
Stiff neck 12 (11%) 1 (4%) 0 2 (12.5%) 0 0 1 (13%) 0 0
Sore throat 23 (22%) 6 (26%) 11 (52%)* 9 (56.25%)* 6 (50%) 4 (40%) 3 (38%) 3 (43%) 0
Swollen glands 2 (2%) 1 (4%) 0 0 0 0 0 0 0
Shortness of breath 71 (66%) 15 (65%) 15 (71%) 13 (81.25%) 8 (67%) 6 (60%) 8 (100%) 7 (100%) 4 (80%)
Palpitation 41 (38%) 11 (48%) 9 (43%) 9 (56.25%) 9 (75%)* 4 (40%) 4 (50%) 3 (43%) 4 (80%)
Cough 55 (51%)* 16 (70%) 14 (67%) 12 (75%) 10 (83%) 5 (50%) 8 (100%)* 7 (100%)* 4 (80%)
Join pain 34 (32%) 7 (30%) 10 (48%) 8 (50%) 6 (50%) 5 (50%) 1 (13%) 1 (14%) 2 (40%)
Muscle soreness 42 (39%) 10 (43%) 13 (62%) 16 (100%)* 7 (58%) 4 (40%) 3 (38%) 3 (43%) 1 (20%)
Fatigue 92 (86%) 19 (83%) 19 (90%) 14 (87.5%) 10 (83%) 8 (80%) 8 (100%) 7 (100%) 5 (100%)
Anorexia 80 (75%) 16 (70%) 16 (76%) 11 (68.75%) 10 (83%) 7 (70%) 8 (100%) 6 (86%) 5 (100%)
Abdominal pain 54 (50%) 11 (48%) 14 (67%) 14 (87.5%)* 8 (67%) 8 (80%) 4 (50%) 2 (29%) 4 (80%)
Nausea 41 (38%) 7 (30%) 7 (33%) 7 (43.75%) 4 (33%) 2 (20%) 1 (13%) 3 (43%) 1 (20%)
Diarrhea 19 (18%) 7 (30%) 4 (19%) 4 (25%) 4 (33%) 1 (10%) 0 1 (14%) 0
Swelling 7 (7%) 1 (4%) 3 (14%) 2 (12.5%) 1 (8%) 0 1 (13%) 0 1 (20%)
Itching 6 (6%) 1 (4%) 3 (14%) 3 (18.75%) 1 (8%) 0 0 0 0
Rash 4 (4%) 1 (4%) 2 (10%) 3 (18.75%)* 1 (8%) 0 0 0 0
Skin lesions 5 (5%) 1 (4%) 1 (5%) 0 0 0 1 (13%) 0 0
Unusual bleeding 0 0 0 0 0 0 0 0 0