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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Nature. 2020 Apr 1;580(7803):396–401. doi: 10.1038/s41586-020-2164-5

Extended Data Figure 3. Molecular MBSHH subtypes.

Extended Data Figure 3.

a. DNA methylation-based UMAP plot of MBSHH with inference of MBSHH subtypes (n = 262).

b. Co-occurring and mutually exclusive somatic gene alterations in ELP1-associated medulloblastoma subtype SHHα.

c. Co-occurring and mutually exclusive somatic chromosomal aberrations in ELP1-associated medulloblastoma subtype SHHα.

d. Recurrent somatic copy-number alterations in ELP1-associated medulloblastoma subtype SHHα.

e. Recurrent somatic copy-number alterations in ELP1-associated SHHα.