Table 2:
Serum biomarkers | Abdominal ultrasound | ARFI | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Years from Fontan | ALT (U/L) Median (range) | AST (U/L) Median (range) | Pit (K/cu mm) Median (range) | APRI | Heterogeneous echotexture Number (%) | Irregular liver margins Number (%) | Mean SWS m/s (Std dev) | |||
1–5 | 33 (20–62) | 45 (29–97) | 253 (177–342) | 0.356 | 1 (6.3%) | 1 (6.3%) | 2.058 (0.236) | |||
5–10 | 32.5 (20–46) | 39.5 (26–54) | 233.5 (165–366) | 0.338 | 2 (22.2%) | 0 (0%) | 2.083 (0.341) | |||
> 10 | 32 (17–54) | 28 (18–51) | 157.5 (78–222) | 0.356 | 7 (50%) | 4 (28.6%) | 2.196 (0.706) | |||
p value | p = 0.934 | p = 0.001 | p <0.000 | p = 0.022 | p = 0.059 | p = 0.996 |
ALT: Alanine transaminase; APRI: AST/platelet index; ARFI: acoustic radiation force impulse; AST: aspartate aminotransferase; Plt: platelet; SWS: shear wave speed