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. Author manuscript; available in PMC: 2020 Aug 17.
Published in final edited form as: Prog Pediatr Cardiol. 2018 Oct 6;53:21–27. doi: 10.1016/j.ppedcard.2018.09.004

Table 2:

Serum biomarkers, abdominal ultrasound and ARFI results based on years from Fontan.

Serum biomarkers Abdominal ultrasound ARFI
Years from Fontan ALT (U/L) Median (range) AST (U/L) Median (range) Pit (K/cu mm) Median (range) APRI Heterogeneous echotexture Number (%) Irregular liver margins Number (%)
Mean SWS m/s (Std dev)
1–5 33 (20–62) 45 (29–97) 253 (177–342) 0.356 1 (6.3%) 1 (6.3%)
2.058 (0.236)
5–10 32.5 (20–46) 39.5 (26–54) 233.5 (165–366) 0.338 2 (22.2%) 0 (0%)
2.083 (0.341)
> 10 32 (17–54) 28 (18–51) 157.5 (78–222) 0.356 7 (50%) 4 (28.6%)
2.196 (0.706)
p value p = 0.934 p = 0.001 p <0.000 p = 0.022 p = 0.059 p = 0.996

ALT: Alanine transaminase; APRI: AST/platelet index; ARFI: acoustic radiation force impulse; AST: aspartate aminotransferase; Plt: platelet; SWS: shear wave speed